The ex-Premier League star was involved in a collision after dropping his children off at school on Monday morning, Trinidad and Tobago’s football association said.
Cheshire Police said it was called to a serious crash involving a van and a Range Rover in the village of High Legh shortly before 8am.
“Sadly the driver of the car, Jlloyd Samuel, 37, from Lymm, died at the scene,” the force said.
“His next of kin have been informed and are currently being supported by specially trained officers.
“The driver of the van, a 54-year-old man, sustained serious injuries and has been taken to hospital for treatment.”
Tributes poured in from the world of football following news of Samuel’s death.
Manchester United star Ashley Young, who played with Samuel at Aston Villa, described him as “such a good guy on and off the pitch and a truly good friend”.
Former Tottenham captain Ledley King said he was “devastated” to lose one of his closest friends and he had exchanged messages with Samuel the night before his death.
Meanwhile, Aston Villa said it will hold a minute’s applause and their players would wear black armbands in tribute to Samuel in their Championship play-off fixture against Middlesbrough on Tuesday night.
We are deeply saddened to hear of the death of our former player Jlloyd Samuel at the age of just 37 in a car accident
— Aston Villa FC (@AVFCOfficial) May 15, 2018
Everybody associated with Bolton Wanderers Football Club is deeply saddened to learn of the passing of our former defender, Jlloyd Samuel.
— Bolton Wanderers FC (@OfficialBWFC) May 15, 2018
The Trinidad and Tobago FA said it extended its “deepest condolences” to Samuel’s family members “both in the UK and here in Trinidad and Tobago”.
Samuel played 199 times for Aston Villa between 1998 and 2007 and represented England at under 18, under 20 and under 21 level.
The full back left Villa Park to join Bolton in 2007, where he played 83 times until 2011.
He also had loan spells at Gillingham and Cardiff City and played twice at international level for Trinidad and Tobago, the country he was born in.
Samuel played football in Iran in his later career, joining Esteghlal in 2011 – where he won the league and cup double – and Paykan in 2014.
Most recently he was player-manager for Egerton FC in the 12th tier of English football.